Skip to main content

Cerebral palsy cord blood trials

Hero Background

Umbilical cord blood therapy for cerebral palsy

This randomised, placebo-controlled, double-blind clinical trial used donated (allogeneic) cord blood in conjunction with the hormone erythropoietin in children with cerebral palsy (CP). The study results showed significant improvements in the motor and cognitive function of these children. The improvements with cord blood were more favourable when the donor was a closer match to the patient, suggesting great potential for autologous (child’s own) cord blood transfusion in patients with CP.

Location: South Korea
Trial design: Safety and efficacy
Status: Completed
Find out more here

Autologous umbilical cord blood reinfusion in children with cerebral palsy

In a larger clinical trial at Duke University researchers are evaluating the effectiveness of autologous (child’s own) cord blood infusion in the treatment of children with CP. This randomised, controlled trial aims to recruit 120 children with CP over a 2 year period. Participants will be given their own cord blood or a placebo to determine the effects on their neurodevelopmental function and quality of life. The study is estimated to be completed in January 2016.

Location: North Carolina, USA
Trial design: Efficacy study
Status: Active - not recruiting
Find out more

Safety and effectiveness of cord blood in cerebral palsy in children

This clinical trial is assessing the safety and effectiveness of an infusion of autologous (child’s own) cord blood in children who have motor disability due to cerebral palsy. The researchers are currently recruiting (up to 40) children between the ages of 1 and 12 years with cerebral palsy with an estimated completion date in July 2015.

Location: Georgia, USA
Trial design: Safety and efficacy
Status: Open - currently recruiting
Find out more